Molecular Neurodegeneration & Neuropathology: Associate Researcher I
Application deadline: April 2023
Organization: Icahn School of Medicine at Mount Sinai, New York, New York
Position Description: We are seeking a highly motivated research assistant for our neuropathology research laboratory. The program is directed by Dr. John F. Crary, MD-PhD, and focuses on the underlying neuropathology and genetics of Alzheimer's Disease and related neurodegenerative disorders (e.g., chronic traumatic encephalopathy, Parkinson’s disease, etc.). The laboratory uses a variety of state-of-the-art techniques, including genomic analysis, single cell RNA-sequencing, stem cell culture, histology, digital neuropathology, confocal microscopy, and optogenetics. Individuals will be trained to deploy these approaches to study brain diseases and gain exposure to challenges associated with therapeutic discovery, biomarker development, and research design. Successful applicants will have opportunities to attend and present at conferences and contribute to publications. The individual will have opportunities to interface with both clinical staff and basic scientists, making the position ideal for someone who is interested in matriculating to MD or PhD programs.
Responsibilities include:
- Performing cell culture techniques including primary fibroblast generation, maintenance of stem cell lines, generation of brain organoid models for downstream experiments and screening assays
- Immunohistochemistry, immunocytochemistry, and fluorescence microscopy for human brain tissue and stem cell projects
- Performing general molecular biology and protein biochemistry techniques e.g., PCR, RT-PCR, isolation of genomic DNA and RNA from cells and brain tissue, western blotting
- Assisting with data collection, entry, and analysis
- Works closely with staff scientists, postdoctoral fellows, and trainees to ensure the success
- Ensure lab conditions and equipment comply with safety procedures and documentation
Requirements:
- This role requires a bachelor’s degree in a science-related discipline, such as neuroscience, biology, chemistry, psychology, etc.
- Applicants must have experience working in a lab environment
- Applicants should have a strong interest in neuroscience and brain research
- Excellent organizational, interpersonal, and communication skills
- Minimum two-year commitment
Time commitment: Full-time
Compensation: $50,000 - $60,000
Apply: To apply, please email your resume (GPA and relevant courses must be listed) and cover letter to margaret.krassner@mountsinai.org, and cc john.crary@mountsinai.org
We're an equal-opportunity workplace. All applicants will be considered for this position without attention to race, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status. Financially disadvantaged candidates from diverse backgrounds are strongly encouraged to apply.