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Research Assistant III | Microscopy and Cell Biology | Varn Lab


The Varn Lab at The Jackson Laboratory for Genomic Medicine is seeking an experienced and highly motivated individual to oversee the wet lab operations of a research program investigating how tumor-microenvironment interactions shape the evolutionary trajectory of diffuse glioma, the most common malignant brain tumor in adults. The Varn Lab integrates genomic and molecular pathology approaches to study how the neurons, glial cells, and immune cells of the brain tumor microenvironment influence the transcriptional output of malignant glioma cells. As part of this work, we are seeking applicants that come from an experimental biology background and are looking to integrate cutting-edge genomic and microscopy techniques to investigate the role of the microenvironment in cancer evolution.   For additional information, visit the Varn Lab’s webpage at jax.org.
The ideal candidate for this role will be motivated, curious, and have an established track record in experimental biology. Candidates will be expected to manage wet lab operations with minimal supervision and collaborate with other labs at The Jackson Laboratory to bring new techniques into the laboratory. Priority will be given to candidates with a training background in cell and molecular biology and immunofluorescence microscopy. Prior experience using in vitro cell line models of disease is essential. Individuals in this position will have access to state-of-the-art resources at The Jackson Laboratory and opportunities will exist to receive on-the-job training in computational analysis of genomic and spatial datasets. Overall, individuals will be well-supported to conduct exciting research that blends the fields of cell biology, microscopy, and computational biology.
Key Responsibilities

  • After training, execute high-dimensional multiplex immunofluorescence experiments including developing antibody panels and microscopically imaging tissue samples
  • Maintain in vitro cell culture models of human cancer
  • Handle, organize, and process human tissue samples
  • Implement and maintain good biosafety practices
  • Collaborate with other labs at JAX to learn techniques and optimize protocols
  • Mentor and supervise trainees in wet lab techniques
  • Assist in writing manuscripts, reports, and funding proposals
  • Present results at lab meetings and institutional symposia
Qualifications

  • Masters in Cell Biology, Molecular Biology, Genetics, or related field and at least 3 years of experience in a cell biology laboratory OR Bachelor’s degree in biological sciences and at least 5 years of experience in a cell biology laboratory
  • Experience using common wet lab and microscopy techniques and maintaining in vitro cell culture models
  • Strong managerial, organizational, and communication skills that will allow for the execution of multiple projects with minimal supervision
  • Ability to drive projects forward and take initiative in solving problems
  • An established understanding and history of using good biosafety practices
  • A personal growth mindset and receptiveness to constructive feedback
  • A desire to work with others both collaboratively and as a mentor
  • Excellent written and oral communication skills to disseminate results and methods to the group
Education Preferred: Master's in Cell, Biology, Molecular Biology, Genetics or related field
Experience Preferred: 3 years or mo of experience
Interested applicants should apply with an updated CV and a cover letter.
 
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About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.